Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Advancing Species Identification in Metagenomic Profiling with MAP2B
MAP2B is a metagenomic profiler that works differently from universal marker or whole genome-based methods for deciphering whole metagenome sequencing, which can significantly remove false identifications and generate highly accurate taxonomic profiling results.
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification
This study presents an optimized proteogenomic workflow for the discovery of neoantigens (in particular RNA-derived neoantigens) in a pan-cancer cohort and sheds light on the entity-agnostic prevalence of HLA-I peptide presentation of RNA processing events for tumor targeting.
One step closer to an Implantable Artificial Kidney
Our team at The Kidney Project chose a biohybrid approach to tissue engineering a universal donor kidney that mimics the tandem filtration-concentration physiology of a healthy kidney. Here, we show that cellular scaffolds can double as immunological barriers between host and allogeneic cells.
Pacific Decadal Oscillation causes fewer near-equatorial cyclones in the north Indian Ocean
Our study finds a remarkable 43% decline in the frequency of low-latitude cyclones (LLCs, originating between 5°N and 11°N) during the post-monsoon season in the north Indian Ocean (NIO) in recent decades (1981-2010) compared to earlier decades (1951-1980).